- #PUR BINDING DIGIPOD MOVIE#
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#PUR BINDING DIGIPOD PDF#
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The expressed Pur open reading frame encodes a protein of 322 amino acids. Analysis with a series of mutated oligonucleotides defines a minimal single-stranded DNA Pur-binding element. We report here the cloning and sequencing of a cDNA encoding a protein with strong affinity for the PUR element. The protein binds preferentially to the purine-rich single strand of this element, PUR.
The human Pur factor binds strongly to a sequence element repeated within zones of initiation of DNA replication in several eukaryotic cells.
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